任意の症例構成比率を確保するための動的割付 A Dynamic Allocation Procedure to Enable to Achieve a Specific Proportion of Sample Sizes

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著者

    • 西 次男 NISHI Tsugio
    • 株式会社ベルシステム24医薬関連ビジネスユニット BELLSYSTEM24, Inc. Medical Support Business Unit

抄録

We showed a dynamic allocation procedure to achieve a specified proportion of sample sizes among treatment groups not only within all patients, but also within patients with strata composed of centers and/or prognostic factors in randomized controlled clinical trials. This procedure allocates a patient to one of treatment groups that are within a pre-specified range from the best balance, as well as the treatment groups with the best balance. When target sample sizes of two treatment groups are the same, Zelen (1974) showed a restriction for a range of obtained sample sizes. Proposed method is an extension of Zelen's restriction to the case of different target sample sizes of more than two treatment groups. This method can introduce randomness into a dynamic allocation procedure keeping comparability among treatment groups.

収録刊行物

  • 計量生物学  

    計量生物学 27(1), 69-79, 2006-06-30 

    The Biometric Society of Japan

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各種コード

  • NII論文ID(NAID)
    10018012993
  • NII書誌ID(NCID)
    AA11591618
  • 本文言語コード
    JPN
  • 資料種別
    SHO
  • ISSN
    0918-4430
  • NDL 記事登録ID
    8007749
  • NDL 雑誌分類
    ZR1(科学技術--生物学)
  • NDL 請求記号
    Z74-B725
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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