整形外科医のためのエタネルセプトの使い方

DOI 参考文献7件

書誌事項

タイトル別名
  • How to Use Etanercept, for Orthopaedic Surgeons

この論文をさがす

抄録

Objective: To report the results of a pilot study of Etanercept without MTX treatment for RA, using the same dosage of Etanercept allowed in Japan as in Europe and the U. S.<BR>Methods: Seven RA patients (one male, six females, ages 54-73 years old; stage 1: one; 4: six; class 1: one; 2: three; 3: three) were given subcutaneous Etanercept twice a week. All RA patients underwent general close inspection including HRCT and a tuberculin test as well as infectious disease screening before Etanercept administration.<BR>Results: Finally, 6 of the 7 RA patients completed this pilot study without severe complications. One of 2 Infliximab invalidity patients canceled this study due to itching and non-effectiveness. Prophylaxis by isoniazide was performed for the patient with a history of pulmonary tuberculosis. Three of the 6 continuative patients were able to reduce their subcutaneous Etanercept to once a week, given reduced RA activity. Above all, early RA was controlled well with only Etanercept. In each case, RA inflammatory activity was controlled by this trial although symptoms of the destroyed joints remained. We tried to do this subcutaneous Etanercept administration if possible from an early stage, to prevent RA joint destruction (operation evasion) .<BR>Conclusion: The pilot study of Etanercept without MTX treatment for RA showed Etanercept to be safe and effective.

収録刊行物

参考文献 (7)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ