Estimation of Reference Intervals for the Shizuoka Prefecture of Japan and Comparison with Those Obtained from Other Two Large-scale Studies of Reference Populations in Japan

• KANNO Takashi

  <I>The Foundation of Hamamatsu Medical Center</I>

• TAUCHI Kazutami

  <I>Shizuoka Medical Service Center MEDIO</I>

• OHGUSHI Yoichi

  <I>The Fundamental Section of Medicine, Tokai University, School of Medicine</I>

• SHIBATA Takeo

  <I>The Fundamental Section of Medicine, Tokai University, School of Medicine</I>

• OGAWA Tetsuhei

  <I>Keiyu-kai, Johto Hospital</I>

• TAKASHIMA Yoshinori

  <I>Depertment of Laboratory, Social Insurance Sakuragaoka General Hospitals</I>

• SUSUYAMA Masahiro

  <I>Shimizu Kosei General Hospitals</I>

• TAKAGI Yoshihiro

  <I>Shizuoka Children's Hospital</I>

抄録

Objective We calculated age- and sex-dependent reference intervals for 10 variables on the basis of health examination data of 156, 565 individuals in Shizuoka prefecture of Japan. We compared these reference intervals with age- and sex-dependent reference intervals calculated from two other large scale studies across the country populations.<BR>Design and Setting Data were obtained from three laboratories, and intervals were calculated by revised Hoffmanns fitting method. On the other hand, Shibata et al. calculated, by a non-linear optimization method (NLO), age- and sex-dependent reference intervals in 5-year age-based increments from data obtained approximately 750, 000 reference individuals from 45 laboratories all around of Japan Moreover, Suka et al. representing the Japan Association of Health Service (JAHS) established reference intervals and collected data from approximately 2.7 million individuals from metropolitan and branch offices in all prefectures of Japan with the basis of NCCLS criteria. We compared with these three large scale age- and sex-dependent reference intervals each others.<BR>Results Reference intervals for all subjects were similar between three studies and especially the serum total cholesterol, uric acid and fasting blood sugar, albumin and lactate dehydrogenase were closely coincided between our study and the other two large scale studies. Levels of serum alkaline phosphatase and postmenopausal increases in this enzyme were similar between our study and Shibata's study.<BR>Conclusion Our findings indicate that if compatibility between laboratories can be established by external quality control analysis, reliable reference intervals could be obtained in large-scale cooperative studies, and the use of these reference intervals by multiple laboratories would be possible.

収録刊行物

• 総合健診

  総合健診 33 (4), 463-469, 2006

  一般社団法人 日本総合健診医学会

キーワード

• Age
• Nonlinear Optimization Method
• Reference Intervals
• Sex
• Tracebility

詳細情報

• CRID: 1390282680174074624
• NII論文ID: 10018040552
• NII書誌ID: AA11592031
• DOI: 10.7143/jhep.33.463
• ISSN: 18844103
• ISSN: 13470086
• Web Site: https://search.jamas.or.jp/link/ui/2007087123
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可