Increasing number of hemodialysis patients treated for ischemic heart disease prior to or at the induction of dialysis therapy

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  • 血液透析導入患者の虚血性心臓合併症に関する検討
  • ケツエキ トウセキ ドウニュウ カンジャ ノ キョケツセイ シンゾウ ガッペイショウ ニ カンスル ケントウ

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Abstract

Increasing number of hemodialysis (HD) patients with end stage renal disease (ESRD) are complicated with ischemic heart disease (IHD) of variable severity by the time of dialysis induction. Understanding the prevalence, the severity and the type of treatment in this population is important for both the dialysis staff and patients in order to start safe and satisfactory dialysis regimen. There were one hundred ten (110) patients with a history of medication, percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) at or prior to dialysis initiation among the 1, 060 patients who started dialysis therapy in our institution during the last 20 years. Because of the small number of with IHD, patients this series was divided into 4 groups according to the year of HD induction, Group I (1983-1987, 10 patients), Group II (1988-1992, 21 patients), Group III (1993-1997, 38 patients) and Group IV (1998-2002, 41 patients). Diabetes mellitus (DM) represents the major background disease among these groups being 5/10 (50%), 10/21 (48%), 21/38 (55%), and 22/41 (54%), respectively. Types of treatment for IHD were medication in 6/10 (60%), 4/21 (19%), 17/38 (45%) and 12/41 (29%); PCI in 3/10 (30%), 12/21 (57%), 15/38 (39%) and 18/41 (44%); CABG in 1/10 (10%), 5/21 (24%), 6/38 (16%) and 11/41 (27%) of patients, respectively. These data show that severe IHD with multiple vessel involvement have increased recently partly because of the high prevalence of DM and the number of older patients. It is, therefore, important to treat or prevent IHD during the maintenance phase of chronic kidney disease to improve the prognosis of HD patients.

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