A Fermented Grain Food Product Extract Ameliorates Tumor Promoter-Induced Skin Oxidative Stress

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著者

    • NAKAMURA Yoshimasa
    • Laboratory of Food and Biodynamics, Nagoya University Graduate School of Bioagricultural Sciences
    • OSAWA Toshihiko
    • Laboratory of Food and Biodynamics, Nagoya University Graduate School of Bioagricultural Sciences

抄録

We demonstrated that a dietary supplement, Antioxidant Biofactor (AOB®), a fermented grain food, inhibits phorbol ester (TPA)-induced inflammatory responses. Pretreatment of mouse skin with ethyl acetate extract of AOB (0.5mg) significantly attenuated the hydrogen peroxide level in mouse skin without inhibition of edema formation. Also, exposure of AOB extract to differentiated HL-60 cells resulted in dose-dependent inhibition of TPA-induced superoxide generation, which was stronger than those of the raw materials of AOB. Our results suggest that AOB is effective for prevention of skin oxidative stress.

収録刊行物

  • Food science and technology research  

    Food science and technology research 11(4), 373-375, 2005-12-01 

    Japanese Society for Food Science and Technology

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各種コード

  • NII論文ID(NAID)
    10018084661
  • NII書誌ID(NCID)
    AA11320122
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    13446606
  • データ提供元
    CJP書誌  J-STAGE 
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