Assisted reproductive technologies and birth defects

• Kohei Shiota

• Shigehito Yamada

Abstract

ABSTRACT  In vitro fertilization (IVF) and other assisted reproductive technologies (ART) are effective treatments for infertility and are widely provided at infertility clinics. Although IVF and related ART procedures are generally considered safe, some studies have suggested an excess occurrence of major malformations, low birth-weight and other perinatal complications in babies conceived by ART. Further, it was recently reported that IVF and intracytoplasmic sperm injection (ICSI) are associated with imprinting disorders in the offspring such as Beckwith-Wiedemann syndrome and Angelman syndrome. Here we review the human and animal studies investigating the potential risks of ART, and discuss the need for further investigation.

Journal

• official journal of Congeital Anomalies Research Association of Japan

  official journal of Congeital Anomalies Research Association of Japan 45 (2), 39-43, 2005

  The Japanese Teratology Society

Keywords

• Developmental Biology
• Embryology
• General Medicine
• Pediatrics, Perinatology and Child Health

Details

• CRID: 1390007458663256576
• NII Article ID: 10018085552
• NII Book ID: AN10066760
• DOI: 10.24540/cgafa.45.2_39
• DOI: 10.1111/j.1741-4520.2005.00061.x
• ISSN: 24331503
• ISSN: 17414520
• ISSN: 00372285
• ISSN: 09143505
• Web Site: https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1741-4520.2005.00061.x
• Web Site: https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1741-4520.2005.00061.x
• Web Site: https://search.jamas.or.jp/link/ui/2006277946
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed