A Case of Chondrosarcoma in the Ethmoid Extending to the Skull Base

DOI 18 References
  • Shiomori Teruo
    Department of Otorhinolaryngology, University of Occupational and Environmental Health, School of Medicine
  • Goto Kyoya
    Department of Otorhinolaryngology, University of Occupational and Environmental Health, School of Medicine
  • Udaka Tsuyoshi
    Department of Otorhinolaryngology, University of Occupational and Environmental Health, School of Medicine
  • Sakabe Akiko
    Department of Otorhinolaryngology, University of Occupational and Environmental Health, School of Medicine
  • Fujimura Kazunobu
    Department of Otolaryngology, Chikuho Rosai Hospital
  • Shiraishi Tsuyoshi
    Department of Otolaryngology, Chikuho Rosai Hospital
  • Ueda Narihisa
    Department of Otorhinolaryngology, University of Occupational and Environmental Health, School of Medicine
  • Ohbuchi Toyoaki
    Department of Otorhinolaryngology, University of Occupational and Environmental Health, School of Medicine
  • Suzuki Hideaki
    Department of Otorhinolaryngology, University of Occupational and Environmental Health, School of Medicine

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Other Title
  • 頭蓋底に進展した篩骨洞軟骨肉腫の1症例

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Abstract

We report a case of chondrosarcoma in the ethmoid extending to the anterior skull base. A 71-year-old woman complained of a right-sided nasal obstruction for one month prior to visiting a regional hospital. Under a tentative diagnosis of an ethmoidal tumor, an endonasal endoscopic biopsy was performed. The histopathological diagnosis was grade-II chondrosarcoma, and the patient was referred to our department. Computed tomography and magnetic resonance imaging revealed a tumor arising in the right ethmoid with extension to the orbit, nasal septum, sphenoid and cribriform plate. Ophthalmological findings were normal. She underwent tumor resection via a lateral rhinotomy combined with an anterior craniotomy followed by an immediate reconstruction of the skull base using a galeopericranial flap. Because the posterior surgical margin was microscopically tumor cell-positive, she was given postoperative radiotherapy (cyber knife). The patient is currently free from disease 6 months after surgery. The epidemiology, pathology, clinical characteristics and treatment of chondrosarcoma of the head and neck are reviewed.

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