CeCl_3・7H_2O/NaI-promoted Efficient Alkylation of Activated Quinoline and Isoquinoline
Active methylene compounds undergo smooth addition to quinolines and isoquinolines activated by chloroformate in the presence of CeCl<SUB>3</SUB>·7H<SUB>2</SUB>O/NaI to afford 2-alkyl-1,2-dihydroquinoline and 1-alkyl-1,2-dihydroisoquinoline, respectively in excellent yields with high selectivity.
- Chemistry letters
Chemistry letters 35(4), 448-449, 2006-04-05
The Chemical Society of Japan