A Simple Iodine-promoted Synthesis of 2-Substituted Benzothiazoles by Condensation of Aldehydes with 2-Aminothiophenol
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Iodine is used to promote the condensation of 2-aminothiophenol with aldehydes in DMF, which affords corresponding 2-substituted benzothiazoles efficiently. Mild and manipulable procedure, use of available and less toxic oxidant, and shorter reaction times are the advantageous features of this method.
- Chemistry Letters
Chemistry Letters 35(4), 460-461, 2006-04-05
The Chemical Society of Japan