海洋産ポリ環状エーテル，シガトキシン類の合成研究

• 高村 浩由

  名古屋大学大学院理学研究科

書誌事項

タイトル別名

• Synthetic Studies of Marine Polycyclic Ether, Ciguatoxins

抄録

More than 20, 000 people suffer annually from ciguatera seafood poisoning in tropical and subtropical areas. The principal causative agents, ciguatoxin and its congeners CTX3C and 51-hydroxyCTX3C are extremely potent neurotoxins that bind to voltage-sensitive sodium channels. The extremely limited availability of these ciguatoxins has hampered the detailed biological studies and preparation of anti-ciguatoxin antibodies for detecting these toxins. Therefore the supply of these compounds by the chemical synthesis has been strongly demanded. Furthermore the unique structural features have attracted the attention of the synthetic chemists. This review has briefly focused on the synthetic studies of ciguatoxins in a convergent manner including a total synthesis.

収録刊行物

• 有機合成化学協会誌

  有機合成化学協会誌 64 (4), 418-419, 2006

  公益社団法人 有機合成化学協会

キーワード

• Organic Chemistry

詳細情報

• CRID: 1390282680287747968
• NII論文ID: 10018131801
• NII書誌ID: AN0024521X
• DOI: 10.5059/yukigoseikyokaishi.64.418
• ISSN: 18836526
• ISSN: 00379980
• 本文言語コード: ja
• データソース種別:
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  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可