Three Cases of Ulcerative Colitis Patients Treated by Antedrug Steroid Hormone Injection Therapy via Appendicostomy

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  • Miyazawa T.
    Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Science
  • Okamoto H.
    Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Science
  • Tani T.
    Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Science
  • Iiai T.
    Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Science
  • Hatakeyama K.
    Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Science
  • Honma T.
    Department of Internal Medicine, Niigata Prefectural Shibata Hospital
  • Sugimura K.
    Division of Gastroenterology, Niigata University Graduate School of Medical and Dental Science
  • Aoyagi Y.
    Division of Gastroenterology, Niigata University Graduate School of Medical and Dental Science

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  • 虫垂ろうからのステロイドａｎｔｅｄｒｕｇ注入療法を施行した潰よう性大腸炎の３例

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Abstract

We present three cases of steroid hormone (SH) dependent total-colitis-type ulcerative colitis (UC) patients who underwent antedrug SH injection therapy via appendicostomy.<BR>Case 1 : A 21-year-old woman. She had suffered from UC for 3 years. An appendicostomy was surgically made, and fluocinonide (FLU) was administered via appendicostomy. Her symptoms abated owing to the administration of FLU, and 25 months after receiving the therapy, she was able to abandon this therapy. Case 2 : A 24-year-old woman. She had suffered from UC for 2 years. Her symptoms abated owing to the administration of FLU, but 24 months after receiving the therapy, she developed colitic arthropathy, and so it became necessary to administer SH. Case 3 : A 25-year-old man. He had suffered from UC for 5 years. This therapy was given to him for 6 months. Because of the narrow lesion of the sigmoid colon, FLU seemed to spread not equally in the large intestine, and it did not work. Therefore, administration of immunosuppressant agents became necessary.<BR>This therapy is effective in total-colitis-type UC, self-medication is possible, and the therapy causes few side effects. Therefore, this therapy seems to be useful for SH dependent total-colitis-type UC patients.

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