A CASE OF PIVKA II-PRODUCING GASTRIC CANCER WITH HEPATIC METASTASIS

• KOMAKI Takamitsu

  Department of Surgery, Social Insurance Kinan Hospital

• NAGAOKA Makio

  Department of Surgery, Social Insurance Kinan Hospital

• YAMABE Kazuo

  Department of Surgery, Social Insurance Kinan Hospital

• MICHIURA Tomonari

  Department of Surgery, Social Insurance Kinan Hospital

• FUJII Ryochi

  Department of Surgery, Social Insurance Kinan Hospital

• NAKANO Noboru

  Department of Surgery, Social Insurance Kinan Hospital

Bibliographic Information

Other Title

• 肝転移を伴ったＰＩＶＫＡ　ＩＩ産生胃癌の１例

Abstract

PIVKA II-producing gastric cancer has rarely been reported. This paper presents a case of PIVKA II-producing gastric cancer with hepatic metastasis, together with a review of the literature.<br> A 77-year-old man, found to have a thoracic aortic aneurysm at a medical checkup in July, was seen at the hospital on September 10, 2004. CT scan revealed a tumor in the S6 of liver as well as a chest aortic aneurysm, and then close exploration of the gastrointestinal organs was conducted. Blood tests showed HCV antibody positive, but no abnormalities in the hepatic function were noted. As for tumor makers, elevations of AFP and PIVKA II were noted. Upper gastrointestinal endoscopy revealed a type 3 like tumor in the posterior wall of the gastric pylorus. A biopsy of the stomach yielded a diagnosis of AFP-producing gastric cancer. AFP-producing gastric cancer with metastatic or primary hepatic carcinoma was diagnosed, and a distal gastrectomy and right hepatic lobectomy were performed on November 2. The pathological diagnoses of gastric and hepatic tumors were adenocarcinoma composed of tubular tissue and acinous pattern of proliferation. Immunostaining tests were positive for both AFP and PIVKA II. Accordingly gastric cancer producing PIVKA II and AFP was diagnosed.

Journal

• Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)

  Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 67 (6), 1279-1284, 2006

  Japan Surgical Association

Keywords

• PIVKA II産生胃癌
• 肝転移
• 治療

Details

• CRID: 1390001204849462656
• NII Article ID: 10018199534
• NII Book ID: AA11189709
• DOI: 10.3919/jjsa.67.1279
• ISSN: 18825133
• ISSN: 13452843
• ISSN: http://id.crossref.org/issn/13452843
• Web Site: http://www.jstage.jst.go.jp/article/ringe1998/67/6/67_6_1279/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2006269066
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed