A Case of Diabetes Mellitus with Polycystic Ovary Syndrome Who Became Pregnant and Delivered Successfully after Improving Insulin Resistance

  • Yoshihara Rie
    Division of Diabetes and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine
  • Someya Yasuhisa
    Division of Diabetes and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine
  • Yokoyama Junichi
    Division of Diabetes and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine
  • Tajima Naoko
    Division of Diabetes and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine

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Other Title
  • 生活習慣是正による減量でインスリン抵抗性が著明に改善し,妊娠,出産に至った多嚢胞性卵巣症候群合併糖尿病の1例
  • 症例報告 生活習慣是正による減量でインスリン抵抗性が著明に改善し,妊娠,出産に至った多嚢胞性卵巣症候群合併糖尿病の1例
  • ショウレイ ホウコク セイカツ シュウカン ゼセイ ニ ヨル ゲンリョウ デ インスリン テイコウセイ ガ チョメイ ニ カイゼン シ ニンシン シュッサン ニ イタッタ タノウホウセイ ランソウ ショウコウグン ガッペイ トウニョウビョウ ノ 1レイ

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Abstract

A 31-year-old woman reporting weight gain and oligomenorrhea for 9 years who married at age 25 was diagnosed at the age of 29 with polycystic ovary syndrome (PCOS). She underwent infertility treatment for two years, but failed to conceive. At age 31, she was diagnosed with diabetes mellitus. Her laboratory data was as follows: BMI, 32.0 kg/m2; HbA1C, 6.4%; HOMA-R, 5.15. Through continuous diet and exercise guidance over 5 months, her laboratory data improved as follows: BMI, 26.6 kg/m2; HbA1C, 5.1%; HOMA-R, 2.15. Fourteen months later, she gave birth at BMI, 26.2 kg/m2, and HbA1C, 4.8%. This illustrates the value of improving insulin resistance through lifestyle changes.

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