Effect of population structure on the amount of polymorphism and the fixation probability under overdominant selection

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Under overdominant selection, mutants substantially contribute to increase the amount of polymorphism. It is also known that under neutrality as the migration rates among demes decrease in a subdivided population, the amount of polymorphism increases along with the increase of the effective population size, <i>N</i><sub>e</sub>. In this study, under overdominant selection the effect of population subdivision on the amount of polymorphism was investigated using the diffusion approximation and the low migration approximation. It was shown that if selection is medium or strong (e.g., <i>N</i><sub>T</sub><i>s</i> > 1, where <i>N</i><sub>T</sub> is the population size and <i>s</i> is the selective advantage of heterozygotes), the nucleotide diversity, π, decreases along with the decrease of <i>Nm</i> against the increase of <i>N</i><sub>e</sub>, where <i>N</i> is the size of demes and <i>m</i> is the migration rate per deme. In addition, the ratio of the nucleotide diversity to the evolutionary rate also decreases along with the decrease of <i>Nm</i>. In some cases the ratio becomes smaller than that expected under neutrality as <i>Nm</i> decreases.<br>

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  • Genes & genetic systems  

    Genes & genetic systems 80(4), 287-295, 2005-08-25 

    The Genetics Society of Japan

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各種コード

  • NII論文ID(NAID)
    10018280241
  • NII書誌ID(NCID)
    AA11077421
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    13417568
  • NDL 記事登録ID
    7681542
  • NDL 雑誌分類
    ZR1(科学技術--生物学)
  • NDL 請求記号
    Z53-W539
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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