Hydrogen Bonding-Based Molecular Recognition by Urea, Thiourea and Guanidine

• Nakanishi Waka

  千葉大学大学院薬学研究院

Bibliographic Information

Other Title

• ウレア，チオウレア，グアニジンを用いた水素結合型分子認識

Abstract

Vast number of valuable metal catalyzed reactions has been developed to date. One of the important roles of the metals is the activation of an electrophile as a Lewis acid. On the other hand, due to environmental and economical demands, metal-free reactions have been attracting much attention. In this review, reactions catalyzed by urea, thiourea and guanidine are introduced. These catalysts have more than two active hydrogens, which can activate an electrophile through double hydrogen bonding. High enantioselectivity is achieved by tuning of their side chains.

Journal

• Journal of Synthetic Organic Chemistry, Japan

  Journal of Synthetic Organic Chemistry, Japan 64 (10), 1073-1074, 2006

  The Society of Synthetic Organic Chemistry, Japan

Keywords

• urea
• thiourea
• guanidine
• hydrogen bonding
• double hydrogen bonding
• double activation
• metal-free
• molecular recognition

Details

• CRID: 1390282680288774784
• NII Article ID: 10018311739
• NII Book ID: AN0024521X
• DOI: 10.5059/yukigoseikyokaishi.64.1073
• ISSN: 18836526
• ISSN: 00379980
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed