Encapsulation of Ferricytochrome <i>c</i> into the Nanoparticle Made from a Natural Polysaccharide: Schizophyllan

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  • Mika Kasuga
    Department of Chemical Process & Environments, Faculty of Environmental Engineering, The University of Kitakyushu
  • Naohiko Shimada
    Department of Chemical Process & Environments, Faculty of Environmental Engineering, The University of Kitakyushu
  • Yoichi Takeda
    Department of Chemical Process & Environments, Faculty of Environmental Engineering, The University of Kitakyushu
  • Seiji Shinkai
    Department of Chemistry & Biochemistry, Graduate School of Engineering, Kyushu University
  • Kazuo Sakurai
    Department of Chemical Process & Environments, Faculty of Environmental Engineering, The University of Kitakyushu

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<jats:title>Abstract</jats:title> <jats:p>A novel protein/polysaccharide complexation was found when unfolded ferricytochrome c (Cyt-c) was mixed with denatured schizophyllan (SPG) and the renaturation of both protein and polysaccharide was carried out simultaneously. Upon the complexation, the Q band was split, indicating that ferric Cyt-c was converted into the ferrous state. The changes in circular dichroism and fluorescence from tryptophan showed that the entire protein conformation was drastically deformed.</jats:p>

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  • Chemistry Letters

    Chemistry Letters 35 (10), 1120-1121, 2006-09-09

    Oxford University Press (OUP)

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