An autopsy case of a hemodialysis patient with multiple amyloidomas of the anus and several other organs
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- Ohta Eriko
- Department of Nephrology, Tokyo Medical and Dental University
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- Chida Yoshiko
- Department of Internal Medicine, Nakano General Hospital
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- Doi Mayumi
- Department of Internal Medicine, Nakano General Hospital
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- Ujiie Kazutomo
- Department of Internal Medicine, Nakano General Hospital
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- Ida Takashi
- Department of Internal Medicine, Nakano General Hospital
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- Ando Minoru
- Department of Nephrology, Tokyo Metropolitan Komagome Hospital
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- Kobayashi Daisuke
- Department of Pathology, Tokyo Medical and Dental University
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- Hirokawa Katsuiku
- Department of Pathology, Tokyo Medical and Dental University
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- Kasuga Takeshi
- Department of Pathology, Nakano General Hospital
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- Sasaki Sei
- Department of Nephrology, Tokyo Medical and Dental University
Bibliographic Information
- Other Title
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- 肛門および多臓器に多発性透析アミロイド腫瘤を呈した血液透析患者の1剖検例
- ショウレイ ホウコク コウモン オヨビ タゾウキ ニ タハツセイ トウセキ アミロイド シュリュウ オ テイシタ ケツエキ トウセキ カンジャ ノ 1 ボウケンレイ
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Abstract
We report an autopsy case of a 69-year-old male with anal amyloid tumor (amyloidoma) who had been treated with hemodialysis for 17 years. The autopsy examination showed that multiple amyloidomas had formed not only on the anus but in the abdominal cavity, subcutaneous tissues and other sites. Immunohistochemical study demonstrated that all of the amyloidomas were stained positive with anti-β2 microglobulin antibody. Although he had a latent IgGκ type monoclonal gammopathy of undetermined significance, the amyloidomas were stained negative with anti-IgG antibody and anti-κ antibody. These findings confirmed that they were dialysis-related amyloidosis due to long-term hemodialysis treatment. Here, we report this rare case of multiple dialysis-related amyloidomas involving several organs including the anus, with reference to autopsy findings.
Journal
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- Nihon Toseki Igakkai Zasshi
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Nihon Toseki Igakkai Zasshi 39 (8), 1293-1297, 2006
The Japanese Society for Dialysis Therapy
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Keywords
Details 詳細情報について
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- CRID
- 1390282679651282816
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- NII Article ID
- 130003875410
- 10018333071
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- NII Book ID
- AN10432053
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- ISSN
- 1883082X
- 13403451
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- NDL BIB ID
- 8084460
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed