A CASE OF PULMONARY MYCOBACTERIUM SHIMOIDEI INFECTION

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  • 肺Mycobacterium shimoidei感染症の1例
  • ショウレイ ホウコク ハイ Mycobacterium shimoidei カンセンショウ ノ 1レイ

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Abstract

A 68 year-old male who was ex-smoker presented with fever and cough. Chest radiograph showed infiltrative shadows in both upper lung fields. A sputum smear for acidfast bacilli was positive. But the isolate was not identified by polymerise chain reaction method. Acid-fast bacilli we re cultured from sputum, but the identification was not done by DNA-DNA hybridization method. Mycobacterium shimoidei was identified by 16S ribosomal RNA sequencing with 98. 42 % matching. Rifampicin, ethambutol, clarithromycin, pyrazinamide, and ciprofloxacin were administered, and the symptom and abnormal shadows on chest radiography improved. And three months later from the initiation of treatment, sputum smear for acid-fast bacilli became negative. Chest CT scan four months after treatments showed decrease of infiltrative shadows. We had treated him for six months, and after that no recurrence occurred.

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