Management of the Pain Associated with Endometriosis: An Update of the Painful Problems

• Ozawa Yuka

  Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine

• Murakami Takashi

  Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine

• Terada Yukihiro

  Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine

• Yaegashi Nobuo

  Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine

• Okamura Kunihiro

  Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine

• Kuriyama Shinichi

  Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine

• Tsuji Ichiro

  Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine

抄録

Endometriosis is a condition characterized by ectopic endometrial tissues located outside of the uterus, most commonly found on the pelvic peritoneum or ovary. Endometriosis, which occurs in 7-10% of women in the general population and 71-87% of women with chronic pelvic pain, is associated with dysmenorrhea, chronic pelvic pain, and infertility. There is considerable debate about the effectiveness of various interventions for endometriosis. This review discusses the benefits and drawbacks of pharmacologic and surgical treatments for the pain associated with endometriosis. Laparoscopic surgery has been demonstrated to relieve the pain associated with endometriosis. Hormonal therapies, such as gonadotropin-releasing hormone (GnRH) analogues or the weak androgen danazol, have also been effective at relieving the pain associated with endometriosis. Oral contraceptives appear to be as effective as GnRH analogues for pain relief. Although both surgical and pharmacologic treatments have been effective for relief of the pain associated with endometriosis, the recurrence rate remains significant. The management of pain associated with endometriosis has thus not been satisfied. Larger unified clinical trials are needed to evaluate the effectiveness of new treatments in managing the pain associated with endometriosis.

収録刊行物

• The Tohoku Journal of Experimental Medicine

  The Tohoku Journal of Experimental Medicine 210 (3), 175-188, 2006

  東北ジャーナル刊行会

キーワード

• endometriosis
• pain management
• meta-analysis

詳細情報

• CRID: 1390001204240583296
• NII論文ID: 10018349583
• NII書誌ID: AA00863920
• DOI: 10.1620/tjem.210.175
• ISSN: 13493329
• ISSN: 00408727
• Web Site: http://www.jstage.jst.go.jp/article/tjem/210/3/210_3_175/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2007200779
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可