Contrast-Enhanced Dynamic Magnetic Resonance Imaging of Primary Pulmonary Leiomyosarcoma

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著者

    • TAGAWA TSUTOMU
    • Department of First Surgery, Nagasaki University Graduate School of Biomedical Sciences
    • ASHIZAWA KAZUTO
    • Department of Radiology, Nagasaki University Graduate School of Biomedical Sciences
    • ABE KUNIKO
    • Department of Pathology, Nagasaki University Hospital
    • TSUTSUI SHIN
    • Department of Radiology, Nagasaki University Graduate School of Biomedical Sciences
    • NAGAYASU TAKESHI
    • Department of First Surgery, Nagasaki University Graduate School of Biomedical Sciences

抄録

An abnormal opacity was found incidentally on chest radiography in a 19-year-old Japanese man with lumbago. Chest computed tomography (CT) revealed a 55 × 40 mm well-defined mass with smooth margins in the lower lobe of the right lung (S6). Contrast-enhanced dynamic CT showed that the lesion was not enhanced, suggesting a cystic lesion, such as a bronchogenic cyst. However, contrast-enhanced dynamic magnetic resonance imaging (MRI) revealed enhancement of the lesion, which had a clear margin and homogenous consistency, suggesting a benign pulmonary solid tumor. Video-assisted thoracoscopic surgery, S6 segmentectomy, was performed, disclosing the lesion to be solid. Histopathologically, the tumor consists of spindle cells with ample eosinophilic cytoplasm arranged in an interlacing pattern. Immunohistochemical staining revealed positive desmin reactivity but was negative for α smooth muscle actin and HHF-35 (muscle specific actin), indicating atypical phenotypic differentiation. The lesion was accordingly diagnosed as leiomyosarcoma with low grade malignancy, and right lower lobectomy was performed. The patient has remained free from recurrence for 18 months without any additional chemotherapy or radiation therapy. Contrast-enhanced dynamic MRI should be carried out to facilitate accurate preoperative diagnosis and selection of the correct surgical plan.

収録刊行物

  • THE TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE  

    THE TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE 210(3), 263-267, 2006-11-01 

    Tohoku University Medical Press

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各種コード

  • NII論文ID(NAID)
    10018349857
  • NII書誌ID(NCID)
    AA00863920
  • 本文言語コード
    ENG
  • 資料種別
    NOT
  • ISSN
    00408727
  • データ提供元
    CJP書誌  J-STAGE 
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