Comparison of Topical Steroid Monotherapy and Combination Therapy Consisting of Topical Steroid and Calcipotriol for Treatment of Psoriasis Vulgaris

• TAKAHASHI Hidetoshi

  Department of Dermatology, Asahikawa Medical College

• HASHIMOTO Yoshio

  Department of Dermatology, Asahikawa Medical College

• IIZUKA Hajime

  Department of Dermatology, Asahikawa Medical College

• SAKAI Hiroyuki

  Asahikawa Kosei Hospital

• KATO Naoki

  Wakkanai City Hospital

• TOBISAWA Shinichi

  Kitami Red Cross Hospital

• KOIKE Katsuya

  Nakashibetsu Town Hospital

• ASANO Kazuhiro

  Asano Clinic of Dermatology

Bibliographic Information

Other Title

• 尋常性乾せんに対するカルシポトリオール軟膏とステロイド外用薬併用治療とステロイド外用単独療法との有効性比較―カルシポトリオール・吉草酸ジフルコルトロン軟膏外用併用療法と吉草酸ジフルコルトロン軟膏単独外用療法との比較試験―
• 治療 尋常性乾癬に対するカルシポトリオール軟膏とステロイド外用薬併用治療とステロイド外用単独療法との有効性比較--カルシポトリオール・吉草酸ジフルコルトロン軟膏外用併用療法と吉草酸ジフルコルトロン軟膏単独外用療法との比較試験
• チリョウ ジンジョウセイカンセン ニ タイスル カルシポトリオール ナンコウ ト ステロイド ガイヨウヤク ヘイヨウ チリョウ ト ステロイド ガイヨウ タンドク リョウホウ ト ノ ユウコウセイ ヒカク カルシポトリオール キッソウサン ジフルコルトロン ナンコウ ガイヨウ ヘイヨウ リョウホウ ト キッソウサン ジフルコルトロン ナンコウ タンドク ガイヨウ リョウホウ ト ノ ヒカク シケン
• ―カルシポトリオール・吉草酸ジフルコルトロン軟膏外用併用療法と吉草酸ジフルコルトロン軟膏単独外用療法との比較試験―

Abstract

Although many studies have shown that active vitamin D₃ ointment is effective for the treatment of psoriasis, to our knowledge there are no studies that directly compare topical steroid monotherapy and combination therapy consisting of topical steroid and active vitamin D₃. The aim of our study was to compare the efficacy, safety, and compliance between diflucortolone valerate ointment monotherapy and combination therapy with weekday diflucortolone valerate and weekend calcipotriol ointment. Psoriasis patients were treated twice daily for 6 weeks with diflucortolone valerate (20 patients) or diflucortolone valerate/calcipotriol (24 patients). Both treatments significantly improved the psoriatic skin with similar clinical efficacy. No side effects were observed during the treatment. Questionnaire administered to patients after the study revealed that compliance and satisfaction with the two treatments were similar. Thus, we concluded that diflucortolone valerate/calcipotriol combination therapy was similarly potent as diflucortolone valerate ointment monotherapy and was a good modality as an alternative to such monotherapy for the treatment of psoriasis.

Journal

• Nishi Nihon Hifuka

  Nishi Nihon Hifuka 68 (1), 76-81, 2006

  Western Division of Japanese Dermatological Association

Keywords

• Dermatology

Details

• CRID: 1390282679274771072
• NII Article ID: 10018351175
• NII Book ID: AN00183881
• DOI: 10.2336/nishinihonhifu.68.76
• ISSN: 18804047
• ISSN: 03869784
• NDL BIB ID: 7864982
• Web Site: http://id.ndl.go.jp/bib/7864982
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I7864982
• Web Site: https://search.jamas.or.jp/link/ui/2006123754
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed