大腸癌術後のフォローアップ　　Ｉ．大腸癌術後再発に関するフォローアップ―大腸癌研究会プロジェクト研究「大腸癌術後のフォローアップに関する研究」の検討結果より―

DOI Web Site 被引用文献7件 参考文献9件

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タイトル別名
  • Follow-up after Curative Resection for Colorectal Cancer: A Study from the Japanese Society for Cancer of the Colon and Rectum
  • A Study from the Japanese Society for Cancer of the Colon and Rectum
  • 大腸癌研究会プロジェクト研究「大腸癌術後のフォローアップに関する研究」の検討結果より

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The aim of this study was to clarify the characteristics of relapse of patients followed up intensively after curative resection for colorectal cancer. We enrolled 5, 317 patients who underwent curative resection at 14 hospitals from 1991 to 1996. The relapse rates of stage I, II, IIIa and IIIb were 3.7%, 12.5%, 24.1% and 40.8%, respectively. The relapse rate in patients with stage I colorectal cancer was constant during the 5-year follow-up. On the other hand, those in other stages increased rapidly during the first 3 years and gradually for the next 2 years. The relapse rate 5 years or later was less than 1 %. As for surveillance tools, the combination of clinical visits, physical examination and tumor marker measurement detected approximately half of the cases of relapse. The earlier the relapse occurred, the worse the prognosis after curative resection for colorectal cancer. The prognoses of the patients with curative resection for relapse were better than those without resection. However, the time to relapse made no difference in prognosis after curative resection for relapse. Further studies will be necessary to validate the efficacy of these intensive follow-up and surveillance tools.

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