Points to Consider on Missing Data へのコメント Comments on Points to Consider on Missing Data

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著者

    • 松井 茂之 MATSUI Shigeyuki
    • 京都大学大学院 医学研究科 社会健康医学系専攻 薬剤疫学分野 Department of Pharmacoepidemiology, Kyoto University School of Public Health

抄録

The "Point to Consider (PtC) on Missing Data" issued by EMEA implicitly postulates strict intention-to-treat analyses and discusses various methods for imputation of missing data, including parametric imputation methods. Imputation may not be relevant to situations after the occurrence of particular events such as a terminating event like death or clinical events that can largely alter the value of the response variable. Possibility of non-ignorable missing mechanisms when adopting parametric methods with ignorable assumptions is also discussed. Lastly, we stress the need for greater efforts in designing and monitoring clinical trials to prevent missing observations.

収録刊行物

  • 計量生物学  

    計量生物学 27, S50-S54, 2006-09-30 

    The Biometric Society of Japan

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各種コード

  • NII論文ID(NAID)
    10018357502
  • NII書誌ID(NCID)
    AA11591618
  • 本文言語コード
    JPN
  • 資料種別
    REV
  • ISSN
    0918-4430
  • NDL 記事登録ID
    8532449
  • NDL 雑誌分類
    ZR1(科学技術--生物学)
  • NDL 請求記号
    Z74-B725
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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