Points to Consider on Missing Dataへのコメント

• 松井 茂之

  京都大学大学院医学研究科社会健康医学系専攻薬剤疫学分野

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タイトル別名

• Comments on Points to Consider on Missing Data
• Points to Consider on Missing Data エ ノ コメント

抄録

The “Point to Consider (PtC) on Missing Data” issued by EMEA implicitly postulates strict intention-to-treat analyses and discusses various methods for imputation of missing data, including parametric imputation methods. Imputation may not be relevant to situations after the occurrence of particular events such as a terminating event like death or clinical events that can largely alter the value of the response variable. Possibility of non-ignorable missing mechanisms when adopting parametric methods with ignorable assumptions is also discussed. Lastly, we stress the need for greater efforts in designing and monitoring clinical trials to prevent missing observations.

収録刊行物

• 計量生物学

  計量生物学 27 (Special_Issue), S50-S54, 2006

  日本計量生物学会

キーワード

• intention to treat
• imputation
• terminating events
• sensitivity analysis
• design

詳細情報

• CRID: 1390001204368476160
• NII論文ID: 10018357502
• NII書誌ID: AA11591618
• DOI: 10.5691/jjb.27.s50
• ISSN: 21856494
• ISSN: 09184430
• NDL書誌ID: 8532449
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8532449
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