A case of MALT lymphoma of the liver treated by RFA and Rituximab

DOI PubMed 6 Citations 13 References
  • HAMADA Maho
    Center for Hepatobiliary Diseases, Matsuyama Red Cross Hospital
  • TANAKA Yoshinori
    Center for Hepatobiliary Diseases, Matsuyama Red Cross Hospital
  • KOBAYASHI Yuichi
    Center for Hepatobiliary Diseases, Matsuyama Red Cross Hospital
  • TAKESHITA Eiji
    Center for Hepatobiliary Diseases, Matsuyama Red Cross Hospital
  • JOKO Kouji
    Center for Hepatobiliary Diseases, Matsuyama Red Cross Hospital

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  • ラジオ波焼灼術とＲｉｔｕｘｉｍａｂ投与を行った肝原発ＭＡＬＴリンパ腫の１例

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Abstract

A 69 years old man was admitted to our hospital for further examinations of the liver tumor October, 2003. No underlying liver disease was found. Two tumors in the liver, 2cm in diameter respectively, were detected by abdominal ultrasonography and MRI scan. Ultrasonogram-guided needle biopsy from the liver tumor showed diffuse infiltration of CD20 positive, small lymphocytes. A distinct single band demonstrating clonal JH gene rearrangement was detected by southern blot analysis using tissues by needle biopsy. Thus, the patient was diagnosed with primary hepatic MALT lymphoma in the normal liver. These tumors were treated with percutaneus radiofrequency ablation (RFA), followed by Rituximab administration. No relapse has been noted until September, 2005.<br>

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