自己免疫性膵炎に自己免疫性血小板減少症を合併した1例 A case of autoimmune pancreatitis complicated with immune thrombocytopenia

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症例は80歳男性.血清アミラーゼ高値で紹介入院.腹部超音波およびCTで膵腫大,内視鏡的逆行性胆管膵管造影で主膵管の狭細化を認め,高IgG血症により自己免疫性膵炎と診断した.入院時より血小板数低値を認め,PAIgG高値,抗血小板抗体陽性,抗核抗体陽性,血清補体値低値より自己免疫性血小板減少症合併例と診断した.プレドニゾロン投与にて両疾患は改善し,投与中止後約1年経過するも両疾患の再燃を認めていない.<br>

A 80-year old man was referred to our hospital because of an elevation of serum amylase level. Diffuse enlargement of the pancreas was detected by abdominal computed tomography, and also diffuse narrowing of the main pancreatic duct was revealed using endoscopic retrograde cholangiopancreatography. The serum level of IgG was elevated to 3450mg/d<i>l</i>. Besides, on the 10th hospital day, petechia developed and the platelet level decreased to 1.5×10<sup>4</sup>/μ<i>l</i>. The platelet-associated IgGC antiplatelet antibody and antinuclear antibody in serum were positive. The levels of serum complements were low. From all these findings the patient was diagnosed as autoimmune pancreatitis complicated with immune thrombocytopenia. The treatment with prednisolone was started, which was effective on each disease. The medication was suspended a year ago, and so far there is no data suggesting the recurrence of autoimmune pancreatitis or immune thrombocytopenia.<br>

収録刊行物

  • 日本消化器病學會雜誌 = The Japanese journal of gastro-enterology

    日本消化器病學會雜誌 = The Japanese journal of gastro-enterology 103(6), 661-666, 2006-06-05

    The Japanese Society of Gastroenterology

参考文献:  11件中 1-11件 を表示

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各種コード

  • NII論文ID(NAID)
    10018364881
  • NII書誌ID(NCID)
    AN00192124
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    04466586
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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