The Status of Lipid Management in 1,836 Patients with Coronary Artery Disease : A multicenter survey to evaluate the percentage of Japanese coronary artery disease patients achieving the target low-density lipoprotein cholesterol level specified by the Japan Atherosclerosis Society

この論文にアクセスする

この論文をさがす

著者

    • NAGASHIMA Hirotaka
    • Heart Institute of Japan, Department of Cardiology (HIJC), Tokyo Women's Medical University
    • KASANUKI Hiroshi
    • Heart Institute of Japan, Department of Cardiology (HIJC), Tokyo Women's Medical University

抄録

To determine the status of lipid management in patients with coronary artery disease (CAD) in Japan, we assessed CAD patients who had been receiving lipid-lowering therapy for six months in a cross-sectional survey conducted between June 2001 and December 2002. We defined the achievement rate as the percentage of patients who achieved the target LDL-C level (< 100 mg/dl) specified by the Japan Atherosclerosis Society (JAS). A total of 1,836 Japanese CAD patients were enrolled. In total, 549 (29.9%) achieved the target level. The achievement rate among those receiving statin therapy was 41.3%, which was significantly higher than that (23.4%) among the patients not receiving statin (<I>P</I> < 0.0001). The rate differed with the type of statin; being 54.7% for atorvastatin, 24.8% for pravastatin, 37.1% for simvastatin, and 27.8% for fluvastatin. A multiple regression analysis revealed that atorvastatin use (<I>P</I> < 0.001), and simvastatin use (<I>P</I> = 0.004) significantly contributed to the achievement of the target LDL-C level. In conclusion, large proportions of CAD patients are not achieving the JAS target and the success rates are not similar among different statin therapies, suggesting that cardiologists should consider a more aggressive lipid-lowering therapy with the appropriate choice of statins in Japanese CAD patients.

収録刊行物

  • Journal of atherosclerosis and thrombosis  

    Journal of atherosclerosis and thrombosis 12(6), 338-342, 2005-12-25 

    Japan Atherosclerosis Society

参考文献:  23件

参考文献を見るにはログインが必要です。ユーザIDをお持ちでない方は新規登録してください。

被引用文献:  5件

被引用文献を見るにはログインが必要です。ユーザIDをお持ちでない方は新規登録してください。

各種コード

  • NII論文ID(NAID)
    10018365201
  • NII書誌ID(NCID)
    AA11018976
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    13403478
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
ページトップへ