Isolated Home Hypertension in the Morning is Associated with Target Organ Damage in Patients with Type 2 Diabetes

• Sakaguchi Kazuhiko

  Division of Internal Medicine, the Harima Hospital of the Ishikawajima Harima Heavy Industries Health Insurance Society, Hyogo, Japan.

• Horimatsu Takahiro

  Division of Internal Medicine, the Harima Hospital of the Ishikawajima Harima Heavy Industries Health Insurance Society, Hyogo, Japan.

• Kishi Minoru

  Division of Internal Medicine, the Harima Hospital of the Ishikawajima Harima Heavy Industries Health Insurance Society, Hyogo, Japan.

• Takeda Akihiko

  Division of Internal Medicine, the Harima Hospital of the Ishikawajima Harima Heavy Industries Health Insurance Society, Hyogo, Japan.

• Ohnishi Yutaka

  Division of Internal Medicine, the Harima Hospital of the Ishikawajima Harima Heavy Industries Health Insurance Society, Hyogo, Japan.

• Koike Takashi

  Division of Internal Medicine, the Harima Hospital of the Ishikawajima Harima Heavy Industries Health Insurance Society, Hyogo, Japan.

• Fujisawa Takashi

  Division of Internal Medicine, the Harima Hospital of the Ishikawajima Harima Heavy Industries Health Insurance Society, Hyogo, Japan.

• Maeda Mitsuo

  Division of Internal Medicine, the Harima Hospital of the Ishikawajima Harima Heavy Industries Health Insurance Society, Hyogo, Japan.

抄録

To investigate the relationship between the blood pressure control level and cardiovascular risk in type 2 diabetic patients, we evaluated home blood pressure, office blood pressure, biochemical data, and carotid echographic and echocardiographic findings in 148 patients with type 2 diabetes. According to the criteria for hypertension in the guidelines of the Japanese Society of Hypertension, we classified patients into a normotensive group with home systolic blood pressure in the morning (morning HSBP) < 135 mmHg and office systolic blood pressure (OSBP) < 140 mmHg, an office hypertension group with a morning HSBP < 135 mmHg and OSBP ≥ 140 mmHg, an isolated home hypertension in the morning group with morning HSBP ≥ 135 mmHg and OSBP < 140 mmHg, and a sustained hypertension group with morning HSBP ≥ 135 mmHg and OSBP ≥ 140 mmHg. In the isolated home hypertension in the morning group, the fasting insulin level, urinary albumin excretion, maximum carotid artery intima-media complex thickness, and left ventricular posterior wall thickness were significantly higher and the coefficient of variation for RR intervals was significantly lower than in the normotensive group. These results suggest that isolated home hypertension in the morning is a risk factor for target organ damage in type 2 diabetic patients.

収録刊行物

• Ｊｏｕｒｎａｌ　ｏｆ　Ａｔｈｅｒｏｓｃｌｅｒｏｓｉｓ　ａｎｄ　Ｔｈｒｏｍｂｏｓｉｓ

  Ｊｏｕｒｎａｌ　ｏｆ　Ａｔｈｅｒｏｓｃｌｅｒｏｓｉｓ　ａｎｄ　Ｔｈｒｏｍｂｏｓｉｓ 12 (4), 225-231, 2005

  一般社団法人 日本動脈硬化学会

キーワード

• Isolated home hypertension
• Type 2 diabetes
• Home blood pressure
• Office blood pressure

詳細情報

• CRID: 1390282679409650816
• NII論文ID: 10018365646
• NII書誌ID: AA11018976
• DOI: 10.5551/jat.12.225
• ISSN: 18803873
• ISSN: 13403478
• ISSN: http://id.crossref.org/issn/13403478
• PubMed: 16141627
• Web Site: https://www.jstage.jst.go.jp/article/jat/12/4/12_4_225/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2006163314
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可