The Relationship between Non-HDL Cholesterol and Other Lipid Parameters in Japanese Subjects

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Plasma non-HDL cholesterol (HDL-C) concentration that is simply estimated from plasma total cholesterol and HDL-C concentrations, without the influence of plasma triglyceride concentration, has been included as a therapeutic target for hypertrigly-ceridemic patients in the most recent National Cholesterol Education Program (NCEP) recommendations. In the present study, we estimated plasma non-HDL-C concentration in Japanese subjects to clarify the correlation of plasma non-HDL-C to other plasma lipid concentrations, and to evaluate the NCEP recommendation. Plasma non-HDL-C concentration has a positive correlation with low-density lipoprotein cholesterol (LDL-C) and triglyceride concentrations. From our analysis, 140 mg/dl of plasma LDL-C concentration, which is the level for the diagnosis of hyper-LDL cholesterolemia, corresponds to 169 mg/dl of non HDL-C concentration. The relationship between plasma non-HDL-C and LDL-C concentrations in Japanese subjects is quite similar to that described in the NCEP guideline. Thus, we suggest that non-HDL-C is a useful risk marker in Japan, as recommended by the NCEP.

収録刊行物

  • Journal of atherosclerosis and thrombosis  

    Journal of atherosclerosis and thrombosis 12(2), 107-110, 2005-04-30 

    Japan Atherosclerosis Society

参考文献:  11件

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各種コード

  • NII論文ID(NAID)
    10018366098
  • NII書誌ID(NCID)
    AA11018976
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    13403478
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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