Hodgkin's disease; Past, Present and Future.

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  • Past, Present and Future

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In the past decades, significant progresses have been made in the field of research on Hodgkin's disease1, 2. Results obtained by the single cell analysis of Reed-Sternberg's cells on tissue sections, radically changed our understanding of this ever-debated disease3. Discovery of disturbed functions in some transcription regulatory factors also much clarified the pathophysiology of this disease. In this paper, a brief history and the molecular mechanisms of Hodgkin's disease so far understood will be reviewed.

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