Spectrum of Malignant Lymphoma in Sarawak General Hospital
Recent epidemiological studies reported changing trend of lymphoid neoplasia in the past few decades. Previous study of lymphomas from East Malaysia from 1981 to 1983 showed a pattern similar to other Asian countries, except for low incidence of peripheral T-cell lymphoma in Sarawak. Current study analyzed materials from 1996 to 1998, with the aim to elucidate possible change in disease pattern, if any, in Sarawak 15 years later. A total of 70 re-confirmed lymphoma cases were classified using WHO proposed list of lymphoid neoplasms. There were 61 (87.1%) non-Hodgkin's lymphoma (NHL) and 9 (12.9%) Hodgkin's lymphoma (HL), and NHL: HL ratio was 7:1. Diffuse large B-cell lymphoma was the most common subtype of NHL (62.3%). There was only one case of T-NHL, lymphoblastic type in the series. The number of Chinese patients in this series was relatively low. Overall EBV association was 8.2% in NHL (60% in Burkitt's type) and 33.3% in HL. Majority of the extra-nodal lymphoma was from gastrointestinal tract (14/35, 40.0%), of which 10 were from the intestines. In conclusion, current study showed extremely low incidence of T-NHL and low EBV association in both NHL and HL. In addition, intestinal lymphomas constitute a large proportion of extra-nodal cases.
- Journal of clinical and experimental hematopathology
Journal of clinical and experimental hematopathology 41(1), 45-49, 2001-05-01
The Japanese Society for Lymphoreticular Tissue Research