Unusual case of cutaneous T-cell lymphoma with a prominent reactive population of B lymphocytes

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著者

    • NOZAWA Yoshihiro
    • Department of Pathology, School of Medicine, Fukushima Medical University
    • TASAKI Kazuhiro
    • Department of Pathology, School of Medicine, Fukushima Medical University
    • OHTSUKA Mikio
    • Department of Dermatology, School of Medicine, Fukushima Medical University
    • IWATUKI Keiji
    • Department of Dermatology, School of Medicine, Fukushima Medical University
    • ABE Masafumi
    • Department of Pathology, School of Medicine, Fukushima Medical University

抄録

A 58-year-old Japanese woman presented an eruption in the region of the back and the upper extremities, a subcutaneous nodule on the right breast, and a left cervical lymphadenopathy. The excision biopsy specimens, of a subcutaneous nodule and a lymph node, showed a vaguely nodular growth pattern comprising a small CD20<sup>+</sup> IgD<sup>+</sup> lymphocyte infiltrate around clusters of medium-sized or large CD3<sup>+</sup> lymphoid cells, in which histological distinction between malignant lymphoma and reactive lymphoid hyperplasia was difficult. Southern-blot analysis revealed the presence of rearranged bands for the beta chain of the T-cell receptor, but not for the immunoglobulin heavy chain. The neoplastic cells were therefore identified to be of T-cell origin. This case represents an unusual cutaneous T-cell lymphoma with a prominent reactive population of B lymphocytes.

収録刊行物

  • Journal of clinical and experimental hematopathology  

    Journal of clinical and experimental hematopathology 41(1), 69-72, 2001-05-01 

    The Japanese Society for Lymphoreticular Tissue Research

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各種コード

  • NII論文ID(NAID)
    10018366957
  • NII書誌ID(NCID)
    AA11556796
  • 本文言語コード
    ENG
  • 資料種別
    NOT
  • ISSN
    13464280
  • データ提供元
    CJP書誌  J-STAGE 
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