INVASIVE DUCTAL CARCINOMA ARISING IN A PHYLLODES TUMOR OF THE BREAST-A CASE REPORT-

  • ODAWARA Hiroki
    Departments of Surgery, National Hospital Organization Takasaki Hospital
  • ISHIDA Tsunehiro
    Departments of Surgery, National Hospital Organization Takasaki Hospital
  • NAGAOKA Hiroshi
    Departments of Surgery, National Hospital Organization Takasaki Hospital
  • OGAWA Akira
    Departments of Pathology, National Hospital Organization Takasaki Hospital
  • HORIGUCHI Jun
    Department of Thoracic and Visceral Organ Surgery, Graduate School of Medicine, Gunma University
  • MORISHITA Yasuo
    Department of Thoracic and Visceral Organ Surgery, Graduate School of Medicine, Gunma University

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Other Title
  • 乳腺葉状腫瘍内に発生した浸潤性乳癌の1例

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Abstract

A 54-year-old woman had been aware of a left breast tumor for 15 years. In December 2003, the patient recognized ulceration and bleeding from the tumor. At the first visit, a 12×11-cm bulged tumor with an ulcer and bleeding was seen on her left breast, with small nodules of the skin around the tumor. Several elastically hard lymph nodes were palpable at the left axilla and supuraclavicular. Core needle biopsy cytology showed invasive ductal carcinoma. The diagnosis of a local advanced cancer of the left breast, T4b N3c M0 Stage III C, was made. Following neoadjuvant chemotherapy at one term, a standard radical mastectomy was performed in May 2004. Pathological examination showed a scirrhous carcinoma that penetrated the center of a benign phyllodes tumor and infiltrated the greater pectoral muscle, suggesting that invasive ductal carcinoma may have originated from inside a benign phyllodes tumor. It is extremely rare for a phyllodes tumor to be associated with a breast cancer on the same time and side of the breast; only 27 cases including our patient have been reported in Japan. Moreover, only 10 cases of a breast cancer that originated from inside a phyllodes tumor have been reported.

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