高AFP血症で発見された胆嚢癌の1例

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  • A CASE OF CARCINOMA OF THE GALLBLADDER FOUND BY A HIGHLEVEL OF SERUMALPHA-FETOPROTEIN

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A 59-year-old woman was admitted to our hospital because of a high level of serum alpha-fetoprotein (AFP) by a checkup. Abdominal US, CT and MR revealed the filling image in the gallbladder, but did not reveal infiltration into the liver and the other organs from the gallbladder. We suspected carcinoma of the gallbladder and an extended resection of the gallbladder was carried out. The tumor measured 4.0cm×3.5cm, was located in the fundus of the gallbladder, and was filled with soft necrotic tissue in the gallbladder. Histopathologically, the tumor was poorly-differentiated adenocarcinoma. Immunohistochemically, the cancer cells were positive for AFP staining. After operation, the serum AFP level was normalized. The patient has been doing well with no evidence of recurrence after 14 months.

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