臨床的に乳癌との鑑別が必要な lymphocytic mastopathy の2例 TWO CASES OF LYMPHOCYTIC MASTOPATHY REQUIRING DIFFERENTIATION FROM BREAST CANCER

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Lymphocytic mastopathyは,間質の繊維化,乳腺小葉の萎縮,リンパ球浸潤を伴う病態で,乳腺症とは別の疾患群とされている.糖尿病や自己免疫疾患を有する患者の乳腺に発生した報告は散在するが,基礎疾患がない患者に本症を生じた報告例は稀である.今回,基礎疾患のない高齢の女性患者で本症と診断した2例を経験した.症例1: 62歳,女性.検診にて右C領域に腫瘤を指摘された.超音波にて内部ほぼ均一で低エコーな腫瘤を認め,マンモグラフィでは局所的非対称陰影を認めた.症例2: 68歳,女性.右D領域に腫瘤を自覚,当科受診となる.超音波にて内部不均一の低エコーを示したが,マンモグラフィでは特に所見を認めなかった. 2症例とも悪性を否定できなかったため摘出生検を施行,本症の診断に至った.本症は臨床上,乳癌との鑑別が困難である場合があり,生検されることが多い.乳腺腫瘤の鑑別診断として本症も念頭に置く必要があると思われた.

Lymphocytic mastopathy is accompanied by interstitial fibrosis, atrophy of the mammary lobules, and lymphocyte infiltration. Sporadic reports of this mastopathy subtype appearing in the mammary glands of patients with diabetes mellitus and autoimmune disease have appeared, however, that in patients without any underlying disease has been rarely reported. We report 2 cases diagnosed as lymphocytic mastopathy that occurred in patients without evidence of underlying disease. Patient 1, a 62-year-old woman, had a breast tumor in the right C area, which was visualized as an almost homogeneous hypoechoic tumor on ultrasonography and a locally asymmetric shadow on mammography. Patient 2, a 68-year-old woman, had a breast tumor in the right D area, which was visualized as a heterogeneous hypoechoic tumor on ultrasonograhy. No particular findings were noted on mammography. Malignancy could not be denied in either case and biopsies were performed, the results of which led to the diagnosis.<br> As it can be difficult to clinically differentiate mastopathy from breast cancer, a biopsy is frequently used. We consider it necessary to take lymphocytic mastopathy into account when making a differential diagnosis of a mammarty tumor.

収録刊行物

  • 日本臨床外科学会雑誌 = The journal of the Japan Surgical Association  

    日本臨床外科学会雑誌 = The journal of the Japan Surgical Association 67(9), 2012-2016, 2006-09-25 

    Japan Surgical Association

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各種コード

  • NII論文ID(NAID)
    10018391574
  • NII書誌ID(NCID)
    AA11189709
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    13452843
  • データ提供元
    CJP書誌  J-STAGE 
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