A CASE OF SMALL CELL CARCINOMA OF THE STOMACH DIAGNOSED PREOPERATIVELY

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  • 術前診断した胃原発小細胞癌の１例

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Abstract

Small cell carcinoma of the stomach is a very rare neoplasm with a poor prognosis. We present a case of small cell carcinoma of the stomach which was diagnosed preoperatively.<br> An 85-year-old woman was found by endoscopic examination to have a type 2 tumor at the upper body of the stomach, which was diagnosed as small cell carcinoma with a biopsy. The patient underwent a total gastrectomy with regional lymph nodes dissection. Surgical findings were T2, N0, H0, P0, M0, and Stage IB. Gross findings of the resected specimen showed a 36×36mm tumor with a submucosal tumor-like appearance in the cross section. Pathological evaluation confirmed pure type of small cell carcinoma (medullary type, INFβ, T2 (MP), ly2, v3, nl, PM(-), DM(-), and Stage II). Immunohisto-chemically, these small cell carcinoma cells were stained for positive for CD56, NSE, synaptophysin, and chromogranin A. Adjuvant chemotherapy was not performed in consideration of her advanced age. Ten months after the operation, multiple liver metastasis was detected by abdominal CT scan. However, the patient was followed in our outpatient clinic without reduction in the quality of life.

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