Osmium Complex Grafted on a Carbon Electrode Surface as a Mediator for a Bioelectrocatalytic Reaction
A novel electrochemical modification method of carbon electrodes with redox active amines is proposed for mediated electron transfer between enzymes and electrodes. Histamine-coordinated Os complex was synthesized as a model redox amine. The electro-oxidation of the complex generated a stable covalent linkage between the nitrogen atom of the amino group and the carbon atom of the electrode surface. The covalent-linked Os complex on the electrode showed a good redox response and a high activity as an electron-transfer mediator between the electrode and a model enzyme: PQQ-dependant water-soluble glucose dehydrogenase.
- Chemistry letters
Chemistry letters 35(11), 1244-1245, 2006-11-05
The Chemical Society of Japan