<I>IN VITRO</I> SUSCEPTIBILITES TO LEVOFLOXACIN AND VARIOUS ANTIBACTERIAL AGENTS OF 18,639 CLINICAL ISOLATES OBTAINED FROM 77 CENTERS IN 2004

YAMAGUCHI KEIZO, OHNO AKIRA, ISHII YOSHIKAZU, TATEDA KAZUHIRO, IWATA MORIHIRO, KANDA MAKOTO, TSUJIO YOSHIKO, KIMOTO HIROYA, NISHIMURA MASAHARU, AKIZAWA KOJI, MATSUDA KEIKO, HAYASHI TASUKU, TOMINAGA MAKOTO, NAKAGAWA TAKUO, TOYOSHIMA SHUNKOH, SUGITA AKIHIRO, ITO TATSUMI, SUWABE AKIRA, YAMAHATA KUMIKO, KAIMORI MITSUOMI, NAKAMURA TOSHIHIKO, KAWAMURA CHIZUKO, KATAYAMA YOSEI, YASUJIMA MINORU, KASAI TAKESHI, KIMURA MASAHIKO, MIKI MAKOTO, NAKANOWATARI SUSUMU, KAKU MITSUO, KANEMITSU KEIJI, KUNISHIMA HIROYUKI, SAKURAI MASANORI, SHIOTANI JOJI, OKADA JUN, YONEYAMA AKIKO, KUMASAKA KAZUNARI, KOIKE KAZUHIKO, KOMINAMI HIDENORI, YAMADA TOSHIYUKI, OGURI TOYOKO, WATANABE KIYOAKI, KOBAYASHI YOSHIO, OHTAKE TERUKO, TOTSUKA KYOICHI, OKAMOTO HIDEYUKI, YAMAZAKI KENICHIRO, OKADA MOTOI, IKARI HIROMI, KUROSAWA NAOMI, MORI MIKIO, KANO ICHINO, NAGANO EIKO, KANNO HARUSHIGE, AIHARA MASANORI, MAESAKI SHIGEFUMI, HASHIKITA GIICHI, MIYAJIMA EIJI, SUMITOMO MIDORI, YAMANE NOBUO, IEIRI TAMIO, ITOH KOUICHI, UCHIDA TAKASHI, MURAKAMI MASAMI, YOMODA SACHIE, TAKAHASHI AYAKO, INUZUKA KAZUHISA, GONDA HIDEO, YAMASHITA TAKANORI, YAMAGUCHI IKUO, FUJIMOTO YOSHINORI, ISHIGO SHIOMI, ASANO YUKO, KAGEYAMA FUMIO, SHAKU ETSUKO, GEMMA HITOSHI, UEMURA KEIICHI, HORII TOSHINOBU, YOSHIMURA HITOSHI, HIRAOKA MINORU, WADA HIDEO, BABA HISASHI, ICHIYAMA SATOSHI, FUJITA SHINICHI, OKABE HIDETOSHI, TATEWAKI KENICHI, MORO KUNIHIKO, YOSHIDA HARUYOSHI, YAMASHITA MASANOBU, FUSHIWAKI TAKESHI, SHIMIZU AKIRA, TAKUBO TAKAYUKI, KUSAKABE TADASHI, TAKAHASHI HAKUO, HEIJYOU HITOSHI, ASAI KOJI, KAWAHARA KUNIMITSU, SANO REIKO, MATSUO SYUJI, KOMATSU MASARU, YUZUKI YOSUKE, IKEDA NORIO, SOMA MASAYUKI, YAMAMOTO TSUYOSHI, KINOSITA SYOHIRO, KAWANO SEIJI, KAGEOKA TAKESHI, HONGO TOSHIHARU, OKA MIKIO, NIKI YOSHIHITO, KUSANO NOBUCHIKA, MIHARA EIICHIRO, NOSE MOTOKO, KUWABARA MASAO, FUJIUE YOSHIHIRO, HINODA YUJI, TANAKA NOBUAKI, OKAZAKI TOSHIRO, MASUDA JUNICHI, TAMINATO TOMOHIKO, NEGAYAMA KIYOSHI, SUGIURA TETSURO, MURASE MITSUHARU, YAMANE NOBUHISA, NAKASONE ISAO, AIZAWA HISAMICHI, HONDA JUNICHI, OKAYAMA AKIHIKO, AOKI YOSUKE, MIYANOHARA HIROAKI, HIRAMATSU KAZUFUMI, HIRAKATA YOICHI, KOHNO SHIGERU, HAMAZAKI NAOTAKA, ONO JUNKO, OKADA KAORU

doi:10.11553/antibiotics1968b.59.428

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2004年に全国77施設から分離された臨床分離株18,639株の各種抗菌薬に対する感受性サーベイランス
2004ネンニゼンコク 77 シセツカラブンリサレタリンショウブンリカブ 18 639カブノカクシュコウキンヤクニタイスルカンジュセイサーベイランス

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Abstract

A total of 18,639 clinical isolates in 19 species collected from 77 centers during 2004 in Japan were tested for their susceptibility to fluoroquinolones (FQs) and other selected antibiotics.The common respiratory pathogens, Streptococcus pyogenes, Streptococcus pneumoniae, Moraxella catarrhalis and Haemophilus influenzaeshowed a high susceptible rate against FQs. The isolation rate of beta lactamase non-producing ampicillin-resistant H. influenzae was approximately three times as large as those of western countries. Most strains of Enterobacteriaceae were also susceptible to FQs. The resistance rate of Escherichia coli against FQs has however been rapidly increasing so far as we surveyed since 1994. The FQs-resistant rate in methicillin-resistant Staphylococcus aureus (MRSA) showed approximately 90% except for 36% of sitafloxacin while FQs-resistant rate in methicillin-susceptible S. aureus (MSSA) was around 5%. The FQs-resistant rate of methicillin-resistant coagulase negative Staphylococci (MRCNS) was also higher than that of methicillin-susceptible coagulase negative Staphylococci (MSCNS), however, it was lower than that of MRSA. In Pseudomonas aeruginosa clinical isolates, 32-34% from UTI and 15-19% of from RTI was resistant to FQs. Acinetobacter spp. showed a high susceptibility to FQs. Although FQs-resistant Neisseria gonorrhoeae have not been increased in western countries, it is remarkably high in Japan. In this survey, isolates of approximately 85% was resistant to FQs.

Journal

The Japanese Journal of Antibiotics

The Japanese Journal of Antibiotics 59 (6), 428-451, 2006

Japan Antibiotics Research Association

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CRID: 1390001205494811136

NII Article ID: 120000809565; 10018449320; 130004396049

NII Book ID: AN00002626

DOI: 10.11553/antibiotics1968b.59.428

COI: 1:STN:280:DC%2BD2s7jsFKksw%3D%3D

ISSN: 21865477; 03682781

NDL BIB ID: 8633076

Web Site: http://hdl.handle.net/2297/5612; https://ndlsearch.ndl.go.jp/books/R000000004-I8633076; https://search.jamas.or.jp/link/ui/2007174899

Text Lang: ja

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<I>IN VITRO</I> SUSCEPTIBILITES TO LEVOFLOXACIN AND VARIOUS ANTIBACTERIAL AGENTS OF 18,639 CLINICAL ISOLATES OBTAINED FROM 77 CENTERS IN 2004

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<I>IN VITRO</I> SUSCEPTIBILITES TO LEVOFLOXACIN AND VARIOUS ANTIBACTERIAL AGENTS OF 18,639 CLINICAL ISOLATES OBTAINED FROM 77 CENTERS IN 2004

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