The current status and problem of platelet transfusion for hematopoietic diseases: results from a questionnaire survey

  • KATO Hidefumi
    Department of Transfusion Medicine, Aichi Medical University
  • HANDA Makoto
    Department of Transfusion Medicine & Cellular Therapy, Keio University School of Medicine
  • TAKAMOTO Shigeru
    Department of Transfusion Medicine, Aichi Medical University

Bibliographic Information

Other Title
  • 造血器疾患における血小板輸血の現状と問題点
  • 臨床研究 造血器疾患における血小板輸血の現状と問題点--アンケート調査結果より
  • リンショウ ケンキュウ ゾウケツキ シッカン ニ オケル ケッショウバン ユケツ ノ ゲンジョウ ト モンダイテン アンケート チョウサ ケッカ ヨリ
  • ―アンケート調査結果より―

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Abstract

We carried out a survey on platelet transfusions performed in hospitals certified by the Japanese Society of Hematology. The average values of the pretransfusion platelet count (trigger value) for the day on which the transfusion was ordered, and the values on each day in the interval between the order and actual transfusion, were compared with the Guidelines. The average trigger value in aplastic anemia and myelodysplastic syndrome patients (A group) (1.41×104l) for the same day on which the transfusion was ordered was higher than the Guideline, whereas those patients with hematological disorders undergoing chemotherapy (B group) and hematopoietic stem cell transplantation (C group), namely 2.08×104l and 2.1×104l, respectively, were acceptable values when compared with the Guidelines. On the other hand, in all groups, the transfusion trigger values at one or two days after ordering were higher than the Guidelines, being 2.56×104l in the A group, 3.15×104l in the B group, and 2.59×104l in the C group. We have tried to formulate platelet count criteria for ordering a transfusion based on one day before the actual transfusion, because these platelet counts on ordering were relatively high. The criteria are 1.0∼1.5×104l in group A, 3.0×104l in group B, and 3.0×104l in group C. In order to perform platelet transfusion according to the Guidelines, the platelet count on ordering should be decreased as we proposed.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 47 (12), 1514-1520, 2006

    The Japanese Society of Hematology

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