位相改良による電子密度図のリファイン [in Japanese] Phase Improvement and Density Modification [in Japanese]
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Before starting model building, the first set of protein phase, which is obtained with the isomorphous replacement method, the multiple wavelength anomalous dispersion method, and/or the molecular replacement method, should be improved by the phase improvement and density modification techniques. An insufficient quality of the electron density map might be a snag for model building. Methods of phase improvement and density modification techniques must usually be performed.
X-RAYS 48(6), 381-386, 2006-12-25
The Crystallographic Society of Japan