切れ込み核や単球様の形態を呈した形質細胞性白血病 Plasma cell leukemia presenting with cleaved nuclei and a monocytoid appearance

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著者

    • 安部 康信 [他] ABE Yasunobu
    • 九州大学大学院医学系研究科病態制御内科学 Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
    • 牟田 耕一郎 MUTA Koichiro
    • 九州大学大学院医学系研究科病態制御内科学 Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University

抄録

A 74-year-old man presented with anemia, thrombocytopenia and leukocytosis with 41% abnormal cells having cleaved and monocytoid nuclei. The bone marrow was infiltrated with 43.6% abnormal cells that were negative for peroxidase staining and positive for PAS staining. Surface antigen analysis revealed no expression of CDs 2, 3, 4, 8, 10, 19, 20, 13 or 33. Serum immunoelectrophoresis detected a monoclonal band, which was identifiable as κ-type IgA protein. Immunostaining also revealed expression of IgA and κ-type in the abnormal cells. The patient was diagnosed as having plasma cell leukemia but the morphological findings were unusual. Surface antigen analysis revealed expression of CD38 later. This case suggests that immunostaining of abnormal cells is required for the differential diagnosis of plasma cell leukemia in leukocytosis.

収録刊行物

  • 臨床血液 = The Japanese Journal of Clinical Hematology  

    臨床血液 = The Japanese Journal of Clinical Hematology 48(1), 64-66, 2007-01-30 

    The Japanese Society of Hematology

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各種コード

  • NII論文ID(NAID)
    10018493122
  • NII書誌ID(NCID)
    AN00252940
  • 本文言語コード
    JPN
  • 資料種別
    SHO
  • ISSN
    04851439
  • NDL 記事登録ID
    8616773
  • NDL 雑誌分類
    ZS21(科学技術--医学--内科学)
  • NDL 請求記号
    Z19-295
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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