Diffuse large B-cell lymphoma の再発時に合併し, rituximab 治療が奏効した赤芽球癆 [in Japanese] Pure red cell aplasia successfully treated with rituximab in a patient with relapsed diffuse large B-cell lymphoma [in Japanese]
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Malignant lymphoma is often accompanied by an autoimmune disorder. Here, we describe a 82-year-old woman with pure red cell aplasia (PRCA) complicated with relapsed diffuse large B-cell lymphoma. Primary treatment involving chemotherapy, continuous oral administration of prednisolone and a single infusion of rituximab was unsuccessful for both diseases, but the following treatments with 3 courses of rituximab alone for once a week dramatically improved the PRCA as well as the lymphoma. As PRCA complicated with lymphoma is rare, the ideal therapeutic strategy has not yet been established for it. Rituximab may be a good alternative for treating such cases.
- Rinsho Ketsueki
Rinsho Ketsueki 48(1), 67-70, 2007-01-30
The Japanese Society of Hematology