小児反復性中耳炎に対する十全大補湯の効果

• 丸山 裕美子

  黒部市民病院耳鼻咽喉科

• 星田 茂

  黒部市民病院耳鼻咽喉科

• 伊藤 真人

  金沢大学大学院医学系研究科脳医科学専攻脳病態医学感覚運動病態学

• 古川 仭

  金沢大学大学院医学系研究科脳医科学専攻脳病態医学感覚運動病態学

書誌事項

タイトル別名

• Effects of the Herbal Medicine "Juzen-taiho-to" on Otitis-Prone Children
• ヤクブツ ショウニ ハンプクセイ チュウジエン ニ タイスル ジュウゼンタイホトウ ノ コウカ

抄録

Juzen-taiho-to (JTT) is known as a herbal medicine that improves immune function. We evaluated whether JTT has a beneficial effect in otitis-prone children. Twenty otitis-prone infants took JTT at 0.1-0.14mg/kg/day twice a day for three months. The medication compliance rate was 85%. The frequency of otitis media purulenta significantly decreased (t-test, p=.000, Wilcoxon signed rank test, p=.000) by the oral administration of JTT. The number of days of fever (t, p=.000, Wilcoxon, p=.000), antibiotic administration (t, p=.002, Wilcoxon, p=.001), hospital visits (t, p=.014, Wilcoxon, p=.005), and emergency hospital visits (t, p=.000, Wilcoxon, p=.000) also showed significant decreases after taking JTT as compared with before.<br>The onset and progression of infection depends on the balance between the reproductive power of microbes and host defense. The effects of JTT on otitis-prone individuals have not been investigated before. JTT is thought to be one of the effective treatments for otitis-prone cases, and avoiding the overuse of antibiotics would prevent the increase of drug-resistant bacteria both in terms of their number and level of resistance.

収録刊行物

• 耳鼻咽喉科臨床

  耳鼻咽喉科臨床 100 (2), 127-135, 2007

  耳鼻咽喉科臨床学会

キーワード

• herbal medicine
• Juzen-taiho-to
• otitis-prone
• immune function
• drug-resistant bacteria

詳細情報

• CRID: 1390001204265045120
• NII論文ID: 10018494852
• NII書誌ID: AN00107089
• DOI: 10.5631/jibirin.100.127
• ISSN: 18844545
• ISSN: 00326313
• NDL書誌ID: 8669565
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8669565
• Web Site: https://search.jamas.or.jp/link/ui/2007135956
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可