Creatinine clearance estimation in the extremely elderly subjects

• Hirayama Shunichi

  Tokyo University of Pharmacy and Life Science

• Kikuchi Reiko

  Department of Geriatric Medicine, Kyorin University, School of Medicine

• Inoue Shinichiro

  Department of Geriatric Medicine, Kyorin University, School of Medicine

• Tsukahara Daisuke

  Department of Geriatric Medicine, Kyorin University, School of Medicine

• Suemitsu Yumi

  Department of Geriatric Medicine, Kyorin University, School of Medicine

• Kobayashi Yoshio

  Department of Geriatric Medicine, Kyorin University, School of Medicine

• Sugiyama Yoichi

  Department of Geriatric Medicine, Kyorin University, School of Medicine

• Hasegawa Hiroshi

  Department of Geriatric Medicine, Kyorin University, School of Medicine

• Kouzaki Koichi

  Department of Geriatric Medicine, Kyorin University, School of Medicine

• Inoue Gosuke

  Department of Internal Medicine, Higashimurayama Nursing Home

• Toba Kenji

  Department of Geriatric Medicine, Kyorin University, School of Medicine

Bibliographic Information

Other Title

• 超高齢者におけるクレアチニンクリアランス推定式の比較検討
• チョウ コウレイシャ ニ オケル クレアチニン クリアランス スイテイシキ ノ ヒカク ケントウ

Abstract

Background: It has been reported that elderly outpatients take at least 6 different kinds of medication.<br> Purpose: To know which formula will best predict creatinine clearance, because 24-hour urine collection is difficult for elderly outpatients.<br> Patients and Methods: We compared four types of formulae (Cockcroft & Gault, Yasuda, Orita, Walser) to estimate creatinine clearance using serum creatinine of 143 elderly inpatients (73 men, 70 women, mean age 82.9±8.6 years old) including 67 extremely elderly people with various underlying diseases.<br> Result: The formula of Cockcroft and Gault showed the best correlation with creatinine clearance in the extremely elderly subjects (r=0.74) as well as in people under 85 years (r=0.76). However, the estimated values of the extremely elderly women were lower than actual creatinine clearance.<br> Conclusion: The formula of Cockcroft and Gault is the best predictive equation of creatinine clearance, except in the extremely elderly women.<br>

Journal

• Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics

  Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics 44 (1), 90-94, 2007

  The Japan Geriatrics Society

Keywords

• Extremely elderly
• Creatinine clearance
• Predicting formula
• Cockcroft & Gault's formula
• Yasuda's formula

Details

• CRID: 1390001205025617792
• NII Article ID: 130004485427
• NII Article ID: 10018513382
• NII Book ID: AN00199010
• DOI: 10.3143/geriatrics.44.90
• NDL BIB ID: 8708930
• ISSN: 03009173
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8708930
• Web Site: https://search.jamas.or.jp/link/ui/2007149501
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed