Polyphenolic Content and Physiological Activities of Chinese Hawthorn Extracts
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- CUI Tong
- College of Food Science and Technology of the Agricultural University of Hebei
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- NAKAMURA Kozo
- Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University
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- TIAN Su
- Department of Nutrition and Food Hygiene, Hebei Medical University
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- KAYAHARA Hiroshi
- Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University
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- TIAN Yi-Ling
- College of Food Science and Technology of the Agricultural University of Hebei
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Abstract
Hawthorn polyphenol (HP) was prepared by ethyl acetate treatment of the ethanol extract (HE) of Chinese hawthorn fruit. The concentrations of 15 polyphenols in the HP, HE, extraction residue (HJ), and a hawthorn leaf extract (HF) were determined by HPLC. For HP, the total content of the 15 polyphenols was 21.4%, comprised of 19.7% of procyanidins, 1.21% of chlorogenic acid, and 0.48% of flavonoids, compared to 2.55% for the HE. The yields of procyanidin monomer, dimer, trimer, tetramer, and pentamer were 50.5%, 30.3%, 23.0%, 14.6%, and 12.5% respectively, and the mean degree of polymerization was reduced to 1.39 (HP) from 1.65 (HE). Seven different physiological actions of the four extracts were investigated. The HP showed strong O2− and •OH scavenging capacities (IC50 values of 6.3 μg/ml and 1.1 μg/ml respectively), as well as selective prolyl endopeptidase inhibition (IC50 of 60 μg/ml). The active constituents appeared to be procyanidins.
Journal
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 70 (12), 2948-2956, 2006
Japan Society for Bioscience, Biotechnology, and Agrochemistry
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Details
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- CRID
- 1390001206477073536
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- NII Article ID
- 10018523826
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- NII Book ID
- AA10824164
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- ISSN
- 13476947
- 09168451
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- NDL BIB ID
- 8596508
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed