Feeding with Both β-Carotene and Supplemental α-Tocopherol Enhances Type 1 Helper T Cell Activity among Splenocytes Isolated from DO11.10 Mice
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β-Carotene and/or supplemental α-tocopherol were fed to DO11.10 mice to investigate their effect on the immune function of naive splenocytes. A high secretion of interleukin-12 and interferon-γ in response to the <I>ex vivo</I> primary antigen presentation occurred only when both were fed. This is consistent with the suppressed immunoglobulin E production under the similar condition described in our previous report.
- Agricultural and Biological Chemistry
Agricultural and Biological Chemistry 70(12), 3042-3045, 2006-12-23
Japan Society for Bioscience, Biotechnology, and Agrochemistry