Antioxidant Activity of Supramolecular Water-Soluble Fullerenes Evaluated by .BETA.-Carotene Bleaching Assay

• TAKADA Hiroya

  Vitamin C60 BioResearch Corporation

• KOKUBO Ken

  Division of Applied Chemistry, Graduate School of Engineering, Osaka University

• MATSUBAYASHI Kenji

  Vitamin C60 BioResearch Corporation

• OSHIMA Takumi

  Division of Applied Chemistry, Graduate School of Engineering, Osaka University

Bibliographic Information

Other Title

• Antioxidant Activity of Supramolecular Water-Soluble Fullerenes Evaluated by β-Carotene Bleaching Assay
• Antioxidant Activity of Supramolecular Water Soluble Fullerenes Evaluated by ベータ Carotene Bleaching Assay

Abstract

We investigated the antioxidant activity of supramolecular water-soluble fullerenes, polyvinylpyrrolidone (PVP)-entrapped C₆₀, and γ-cyclodextrin (CD)-bicapped C₆₀, based on comparable β-carotene bleaching assay. Antioxidant activity against reactive oxygen species (ROS) generated by three different methods, (i) autoxidation of linoleic acid, (ii) hydrogen peroxide promoter, and (iii) photoirradiation, was evaluated as percent of inhibition relative to a control experiment in view of the bleaching rate constant (k_obs) as well as the persistent absorbancy of β-carotene. Water-soluble fullerenes exhibit significant inhibitory effects on the oxidative discoloration of β-carotene in any system.

Journal

• Bioscience, Biotechnology, and Biochemistry

  Bioscience, Biotechnology, and Biochemistry 70 (12), 3088-3093, 2006

  Japan Society for Bioscience, Biotechnology, and Agrochemistry

Keywords

• antioxidant activity
• fullerene
• reactive oxygen species
• radical scavenger

Details

• CRID: 1390282681453820544
• NII Article ID: 10018524380
• NII Book ID: AA10824164
• DOI: 10.1271/bbb.60491
• COI: 1:CAS:528:DC%2BD2sXktVKisQ%3D%3D
• ISSN: 13476947
• ISSN: 09168451
• ISSN: http://id.crossref.org/issn/00032697
• NDL BIB ID: 8597108
• PubMed: 17151439
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8597108
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.60491
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• Abstract License Flag: Disallowed