Effects of Dietary myo-Inositol, D-chiro-Inositol and L-chiro-Inositol on Hepatic Lipids with Reference to the Hepatic myo-Inositol Status in Rats Fed on 1,1,1-Trichloro-2,2-bis (p-chlorophenyl) Ethane

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  • OKAZAKI Yukako
    Department of Human Life Sciences Education, Graduate School of Education, Hiroshima University
  • SETOGUCHI Tomoyasu
    Department of Human Life Sciences Education, Graduate School of Education, Hiroshima University
  • KATAYAMA Tetsuyuki
    Department of Human Life Sciences Education, Graduate School of Education, Hiroshima University

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  • Effects of Dietary myo-Inositol, D-chiro-Inositol and L-chiro-Inositol on Hepatic Lipids with Reference to the Hepatic myo-Inositol Status Rats Fed on 1,1,1-Trichloro-2,2-bis (p-chlorophenyl) Ethane
  • Effects of Dietary<i>myo</i>-Inositol,<scp>D</scp>-<i>chiro</i>-Inositol and<scp>L</scp>-<i>chiro</i>-Inositol on Hepatic Lipids with Reference to the Hepatic<i>myo</i>-Inositol Status in Rats Fed on 1,1,1-Trichloro-2,2-bis (p-chlorophenyl) Ethane

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Abstract

The effects of dietary 0.2% inositol stereoisomers on the hepatic lipids and myo-inositol (MI) status in rats fed with 1,1,1-trichloro-2,2-bis (p-chlorophenyl) ethane (DDT) were investigated. Dietary MI reduced the hepatic lipids in the rats fed with DDT. Dietary D-chiro-inositol (DCI) and L-chiro-inositol (LCI) both had a promoting effect on the increase in hepatic lipids due to DDT feeding. Dietary MI enhanced the hepatic free MI level and the phosphatidylinositol/phosphatidylcholine ratio, but dietary DCI reduced the level and ratio.

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