Oxygenases and dehalogenases: molecular approaches to efficient degradaiton of chlorinated environmental pollutants

• FURUKAWA Kensuke

  Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University

書誌事項

タイトル別名

• Oxygenases and Dehalogenases: Molecular Approaches to Efficient Degradation of Chlorinated Environmental Pollutants

抄録

Microbial oxygenases and dehalogenases are key enzymes in the degradation of highly chlorinated compounds, which often become significant environmental pollutants. Oxygenases engineered by the methods of directed evolution exhibit enhanced degradation of PCBs and other chlorinated solvents such as trichloroethene and pentachloroethane. Dehalorespiration is an efficient dechlorination mechanism that is coupled with energy-yielding phosphorylation. Recently, a variety of chloroethene-dehalorespiring anaerobes have been isolated, and their reductive dehalogenases have been characterized in biochemical and genetic bases. This review describes our recent studies on dioxygenases and reductive dehalogenases.

収録刊行物

• Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ

  Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ 70 (10), 2335-2348, 2006

  公益社団法人 日本農芸化学会

キーワード

• dioxygenase
• reductive dehalogenase
• directed evolution
• hybrid enzyme
• dehalorespiration

詳細情報

• CRID: 1390282681453863296
• NII論文ID: 10018525300
• NII書誌ID: AA10824164
• DOI: 10.1271/bbb.60218
• ISSN: 13476947
• ISSN: 09168451
• NDL書誌ID: 8523661
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8523661
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.60218
• 本文言語コード: en
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