Utilization Study of Stems and Leaves of Tienchi Ginseng(1)Anti-Hypertensive Effect of Stems and Leaves of Tienchi Ginseng on Stroke-Prone Spontaneously Hypertensive Rat (SHRSP)

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  • YANAI Kazuhiro
    R & D, Banjo Foods Co., Ltd. Graduate School of Nutritional and Enviromental Sciences, COE Program in the 21st Century, University of Shizuoka
  • SATO Kazumasa
    R & D, Banjo Foods Co., Ltd. Graduate School of Nutritional and Enviromental Sciences, COE Program in the 21st Century, University of Shizuoka
  • MASUDA Shuichi
    Graduate School of Nutritional and Enviromental Sciences, COE Program in the 21st Century, University of Shizuoka
  • IKEDA Masahiko
    Institute for Environmental Sciences, University of Shizuoka College of Environment and Disaster Research, Fuji Tokoha University
  • KINAE Naohide
    Graduate School of Nutritional and Enviromental Sciences, COE Program in the 21st Century, University of Shizuoka

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  • Utilization Study of Stems and Leaves of Tienchi Ginseng. I. Anti-Hypertensive Effect of Stems and Leaves of Tienchi Ginseng on Stroke-Prone Spontaneously Hypertensive Rat (SHRSP)

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Tienchi ginseng tea was prepared from stems and leaves of Tienchi ginseng which is a special product in China. The increase in systolic blood pressure (SBP) was significantly inhibited by the consumption of a 4% this tea solution as drinking water from the prehypertensive stage (6 weeks of age) in male stroke-prone spontaneously hypertensive rats (SHRSP). A similar intake from the hypertensive stage also showed an anti-hypertensive effect. In contrast, a similar intake had no effect on SBP of normotensive Wistar Kyoto rats. We found that the rhizome of Tienchi ginseng contained two types of saponin: 20(s)-protopanaxadiol (PPD) such as ginsenosides Rb1 and Rd having a hypotensive effect, and 20(s)-protopanaxatriol (PPT) such as ginsenosides Rg1 and Re having a hypertensive effect. In contrast, the tea sample contained PPD and gamma-aminobutyric acid (GABA), but no PPT. These results suggest that drinking this tea infusion would be useful for controlling hypertension.

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