Effects of Chlorogenic Acid and Its Metabolites on Spontaneous Locomotor Activity in Mice

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著者

    • Ohnishi Ryoko OHNISHI Ryoko
    • Department of Pharmacognosy, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
    • Ito Hideyuki ITO Hideyuki
    • Department of Pharmacognosy, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
    • SHINOMIYA Kazuaki
    • Department of Pharmacology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
    • KAMEI Chiaki
    • Department of Pharmacology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
    • HATANO Tsutomu
    • Department of Pharmacognosy, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University

抄録

Chlorogenic acid possessed a weak caffeine-like psychostimulant property when assessed for its effect on spontaneous locomotor activity in mice. In the evaluation of the effects for the major metabolites of chlorogenic acid which were detected upon incubation with rat feces and/or excreted in urine after oral administration to rats, caffeic and <I>m</I>-coumaric acids were found to be the principal active metabolites, while the others contributed little to this caffeine-like psychostimulant activity.

収録刊行物

  • Bioscience, biotechnology, and biochemistry  

    Bioscience, biotechnology, and biochemistry 70(10), 2560-2563, 2006-10-23 

    Japan Society for Bioscience, Biotechnology, and Agrochemistry

参考文献:  12件

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各種コード

  • NII論文ID(NAID)
    10018526235
  • NII書誌ID(NCID)
    AA10824164
  • 本文言語コード
    ENG
  • 資料種別
    NOT
  • ISSN
    09168451
  • NDL 記事登録ID
    8524569
  • NDL 雑誌分類
    ZR7(科学技術--農林水産--農産) // ZR2(科学技術--生物学--生化学) // ZP1(科学技術--化学・化学工業)
  • NDL 請求記号
    Z53-G223
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
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